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There have been attempts to stimulate the dopaminergic
2019-11-25
There have been attempts to stimulate the dopaminergic system to influence cognition in women around menopause who have subjective complaints about their cognition by Epperson et al. (Epperson et al., 2011, Epperson et al., 2015). In perimenopausal and postmenopausal women, Epperson et al. found tha
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br Acknowledgements br Introduction In
2019-11-25
Acknowledgements Introduction In Arabidopsis thaliana (L.) Heynh, there are at least four copies of the caseine kinase-like gene Ck1, which is involved in peptide phosphorylation in mammals [1]. These genes are distributed on CA074 1, 2, 4, and 5. A similar number of copies for Ck1 have been
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To avoid the difficulty of the
2019-11-25
To avoid the difficulty of the nonsmooth constraints, a sequence of smooth problems by using smoothing functions have been progressively approximated this nonsmooth problem. To date, there have been many smoothing functions, such as perturbed Fischer–Burmeister (FB), Chen–Harker–Kanzow–Smale (CHKS),
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Recent studies have shown that
2019-11-25
Recent studies have shown that the extracellular regulated protein kinase 1 and 2 (ERK1 and ERK2), commonly referred to collectively as ERK 1/2, are members of the mitogen-activated protein kinase (MAPK) family. This family of kinases transport signals from the surface of the cell to the nucleus, th
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Glycolysis is important to maintain the vital functions of
2019-11-25
Glycolysis is important to maintain the vital functions of T. gondi. Extracellular T. gondii shift its Tubastatin A metabolism towards glycolysis, based on the observation that a relocation of glycolytic enzymes from the cytosol to the pellicle occurs at the time when tachyzoites egress from host ce
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Several studies on the collagen receptor DDR have revealed
2019-11-25
Several studies on the collagen receptor DDR1 have revealed a defined collagen signaling pathway that causes cell scattering and cadherin switching. As mentioned earlier, DDR ASP1517 mg on collagens are distinct from integrin binding sites; therefore, the same collagen protein can bind to DDR and i
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think about them. We also performed a correlation analysis i
2019-11-25
We also performed a correlation analysis independent of annotated gene sets to identify potentially novel genes that are co-expressed with DHODH. Using the top 100 DHODH co-expressed genes in COAD, LGG, STAD, and PAAD diseases, we identified four common genes across all four diseases (Fig. 9). These
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br Discussion The present study found
2019-11-25
Discussion The present study found cholinesterase activity in Saccostrea sp. to vary significantly among three tissue types (digestive gland, gills, adductor muscle) and to respond differentially to four toxicants, three of which were non-organophosphates. Furthermore, a comparison of enzyme acti
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br Introduction Myotonic dystrophy dystrophia myotonica DM
2019-11-22
Introduction Myotonic dystrophy (dystrophia myotonica, DM) is an autosomal dominant disorder and the most common form of inherited muscular dystrophy in adults [1]. DM is characterised by a wide range of symptoms, including myotonia, progressive muscle loss, cataracts, cardiac conduction defects,
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There exists a glucose residue in the structure of Acid
2019-11-22
There exists a glucose residue in the structure of 5. Acid hydrolysis (Supplementary data) followed by TLC comparison with the reference compound as well as GC–MS analysis (l-cysteine methyl ester hydrochloride derivative: tR=22.22min for glucose residue of 5 and 22.46min for the reference compound)
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br Results br Discussion The most relevant overall finding
2019-11-22
Results Discussion The most relevant overall finding was that DDR1 is present in myelin and is probably synthesized by oligodendrocytes. This result was supported by three different approaches. First, we detected presence of DDR1 mRNA in myelin by ISH. Second, the pattern of DDR1 immunostainin
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In this study for the first time
2019-11-22
In this Butyrolactone 3 synthesis study, for the first time, we demonstrated that herb-derived LFS-01 induces concomitant mitophagy and apoptosis in lymphoma cells. Through various biochemical studies, we showed that LFS-01 directly targets the sulfhydryl (-SH) group of a conserved cysteine in the
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br Acknowledgements The study was supported by
2019-11-22
Acknowledgements The study was supported by grant no. 501-003-11043 from the Institute of Psychiatry and Neurology in Warsaw. The authors thank Mrs. Ala Biegaj for the excellent technical assistance. Introduction In an effort to identify hIFN receptor molecules encoded by a gene(s) within hum
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In conclusion our study has demonstrated that PGE stimulates
2019-11-22
In conclusion, our study has demonstrated that PGE2 stimulates expression of survivin in hepatocellular carcinoma cells. Although there are 4 subtypes of EP receptors, the EP1 receptor appears to be the predominant receptor that regulates PGE2-induced expression of survivin, mainly through trans-act
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Introduction The COMT gene is located on
2019-11-21
Introduction The COMT gene is located on chromosomal band 22q11.2, extends over 28 kb, contains six exons, and encodes for catechol-O-methyl-transferase (Weinshilboum and Raymond, 1977; Grossman et al., 1992; Lundström et al., 1995; Bearden et al., 2005). This enzyme plays a major role in regulatio
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