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Long marginalised as a disorder confined
2019-06-24
Long marginalised as a disorder confined to specific racial groups, sickle-cell disease is now assuming its rightful place as a major global public health problem. Most patients in the Americas, the Caribbean, and much of Europe have been of one racial group, which led to the common misconception th
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Mexiletine HCl what The patient began CODOX M IVAC with ritu
2019-06-24
The patient began CODOX-M/IVAC with rituximab [2]. PET and BM after 2 cycles showed complete remission (CR) and this was confirmed 3 and 6 months later after he completed the full treatment course. There was no delay in administration of each cycle (average: 19 days, 16–21). Eight months after thera
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A year old woman was referred to
2019-06-24
A 77-year-old woman was referred to our medical center for second opinion for refractory CMML-2. She had been incidentally found to have mild leukocytosis, anemia, and thrombocytosis on routine laboratory analysis. At diagnosis her white blood cell count (WBC) was 12×10/L, hemoglobin was 10.8g/dL, a
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Although high and variable frequencies
2019-06-24
Although high and variable frequencies of sickle cell trait in different ethnic groups in Uganda have been reported previously, those data were from around 70 years ago and were based on small sample sizes. Thus, the findings of Ndeezi and colleagues provide a contemporary overview that is nationall
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Ante la necesidad de unas reglas
2019-06-21
Ante la necesidad de unas reglas o códigos SKF 86002 dihydrochloride partir de los cuales evaluar la producción de los decadentistas, el autor del artículo se lamenta de su inexistencia: “¿Dónde está el código de los decadentistas? No le tienen porque en vez de reglas lo que ellos practican es la vi
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br The study by Jesse Berman and colleagues
2019-06-21
The study by Jesse Berman and colleagues published in is the first to systematically analyse the risk of hospital admissions and mortality associated with drought periods in the USA. As the authors state, this is an understudied topic, but of great concern in the USA and globally as climate chang
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Our group then carried out
2019-06-21
Our group then carried out a study to determine the substrate sites and arrhythmogenic mechanisms of the BrS [29]. We found that all our BrS patients had abnormal low voltage, fractionated late potentials exclusively clustering in the anterior aspect of the RVOT epicardium and not seen anywhere else
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The acute effects of goserelin on
2019-06-21
The acute effects of goserelin on bone have also been evaluated by prospective trials of goserelin+/− adjuvant tamoxifen. The Zoladex in Premenopausal Patients trial randomized 89 women with early breast cancer to goserelin+/− tamoxifen, tamoxifen alone and no endocrine therapy. After 2 years of tre
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Atrial fibrillation is the most common atrial
2019-06-21
Atrial fibrillation is the most common atrial arrhythmia studied in BrS [3–14]. The prevalence of AF has been reported to be higher in patients with BrS than in the general buy Cinobufagin of the same age [15,16]. Earlier studies reported an approximately 10–50% prevalence of spontaneous, clinical
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br Update on the diagnosis
2019-06-21
Update on the diagnosis of ERS ERS is generally diagnosed in patients who display ER in the inferior and/or lateral leads presenting with aborted cardiac arrest, documented VF, or polymorphic VT. Consistent with the recent consensus report on ERP [24], ER is recognized if (1) there is an end QRS
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The presence of the anthelmintic levamisole
2019-06-21
The presence of the anthelmintic levamisole is also worrying because it has been withdrawn from many markets for human use owing to its association with agranulocytosis. The recent epidemic of necrotising vasculitis resulting from “cutting” cocaine with levamisole suggests links between criminals wh
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br Discussion Intriguingly in a case report about
2019-06-20
Discussion Intriguingly, in a case report about elevation of skeletal enzymes in ultramarathon runners, the CK level reached its peak value one day after the run, had a ∼4-day plateau, and began to decline after a few more days. The sustained increase of plasma CK in this athlete was quite diffe
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br Conflict of interest br
2019-06-20
Conflict of interest Introduction The use of implantable defibrillation devices such as an implantable cardioverter–defibrillator (ICD) or a cardiac resynchronization therapy device with a defibrillator (CRT-D) is the primary therapy for improving prognoses of patients with life-threatening ve
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br Discussion The cardiac manifestations of organophosphorus
2019-06-20
Discussion The cardiac manifestations of organophosphorus poisoning are well known, involving various electrocardiographic abnormalities that may range from sinus tachycardia to ST elevation. Such most common abnormalities are sinus bradycardia, prolonged QT interval, and ST elevation [2–4]. Most
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br Materials and methods This study
2019-06-20
Materials and methods This study included WCD patients with high risk of SCD but did not meet the eligibility criteria for immediate MnTBAP Chloride of an implantable cardioverter defibrillator (ICD). Current guidelines endorse indications for WCD therapy [5]. Patients with low left ventricular
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